Browse the evidence

Subjects increased their daily walking distance by 3.2 km above pre-study levels.

Encouraging increased walking can be an effective component of weight management programs.

Semaglutide led to a weight reduction of 9.21 kg in the study population.

Semaglutide may assist in significant weight loss for patients in this demographic.

Combined nutrition and exercise interventions significantly reduced body weight by 2.13 kg (95%CI, -3.07 to -1.19) in adults with cancer.

Practitioners can consider combined nutrition and exercise interventions as effective strategies for weight management in cancer patients.

Combined nutrition and exercise interventions significantly reduced fat mass by 2.06 kg (95%CI, -3.02 to -1.09) in adults with cancer.

Practitioners can utilize combined nutrition and exercise interventions to effectively reduce fat mass in cancer patients.

HMB-FA+ATP supplementation resulted in statistically significant changes in muscle mass compared to placebo.

Supplementing with HMB-FA and ATP may enhance muscle mass gains in individuals already engaged in resistance training.

Recent guidelines emphasize the importance of diagnosing and treating obesity to prevent CVD.

Clinicians should follow guidelines to effectively manage obesity in patients to reduce CVD risk.

Nutrient timing is a strategy for enhancing muscular adaptations and athletic performance.

Practitioners should consider nutrient timing as a potential strategy for improving muscle adaptations.

The concept of a 'postworkout anabolic window of opportunity' suggests a limited time after training to optimize muscle protein accretion.

Practitioners should be aware of the proposed timing for nutrient consumption post-workout to enhance muscle protein synthesis.

Higher carbohydrate intake was associated with lower CVD risk, with the lowest risk for quintile 3 (41.0%–44.3% energy as carbohydrate) versus quintile 1 (<37.1% energy as carbohydrate) (OR 0.56, 95% CI 0.35 to 0.91, p=0.02).

Practitioners may consider recommending moderate carbohydrate intake for reducing CVD risk in this population.

Worksite wellness programs (WWPs) increased intake of fruits and vegetables (F&amp;V), especially fruits.

Practitioners can implement WWPs to enhance fruit and vegetable consumption among employees.

WWPs reduced BMI by a mean of -0.64 kg/m² for interventions lasting less than 12 months and -0.16 kg/m² for those lasting 12 months or more.

Practitioners should consider the duration of WWPs when aiming for BMI reduction.

WWPs reduced waist circumference (WC) by a mean of -2.03 cm.

Implementing WWPs can lead to significant reductions in waist circumference.

A national 10% price reduction on fruits, vegetables, nuts, and whole grains is estimated to prevent 19,600 CMD deaths/year.

Implementing a 10% price reduction on healthy foods could significantly reduce CMD mortality.

Whey protein supplementation significantly attenuated post-exercise blood levels for biomarkers of muscle damage compared to water-only.

Whey protein may be beneficial for reducing muscle damage after intense exercise.

Suboptimal diet is the leading risk factor for poor health in nearly every region.

Health practitioners should prioritize addressing dietary issues as a key factor in health.

Maintainers of weight loss in the MedWeight study sustained a 21% weight loss for over four years.

Practitioners can note that long-term weight loss maintenance is achievable with significant initial weight loss.

5-10% weight loss leads to significant improvement in glycemic control, lipids and blood pressure.

Weight loss of 5-10% should be targeted to improve health outcomes in patients with type 2 diabetes.

There is good evidence for the efficacy and tolerability of approved anti-obesity pharmacotherapies in individuals with T2DM.

Clinicians should consider approved anti-obesity medications as part of treatment for patients with T2DM.

A weight-centric therapeutic approach is rational to improve glycemic and other metabolic outcomes in patients with T2DM.

Adopting a weight-centric approach can enhance treatment outcomes for T2DM patients.

Incretin hormone agonists offer substantial weight reduction and cardiometabolic benefits.

Practitioners can consider incretin hormone agonists as effective options for obesity management.

Pre-exhaustion training allows for a greater training volume.

Practitioners can implement pre-exhaustion training to enhance training volume.

Pre-exhaustion training is used to enhance muscular adaptations.

Practitioners can utilize pre-exhaustion to potentially improve muscle growth.

Eccentric actions have the greatest effect on muscle hypertrophy.

Practitioners may consider incorporating eccentric actions into training regimens to enhance muscle growth.

Eccentric overload training could enhance muscular growth when supplemented with resistance training.

Incorporating eccentric overload training into resistance programs may lead to greater muscle growth.