Browse the evidence

Women had a higher increase than men in specific average training load of upper limb exercises during both phases of training.

Practitioners should focus on gender-specific adaptations in upper limb training when designing programs.

Egg consumption is associated with a 38% lower risk of excessive body fat in females.

Promoting egg consumption in females may aid in managing body fat levels.

There are significant dose-response relationships between egg consumption and overweight with excessive body fat/central obesity in females.

Increasing egg intake may be beneficial for reducing body fat and obesity risk in females.

Both the SMA and control groups experienced a mean drop in fasting blood glucose of 6 mg/dL.

Both interventions may help in managing blood glucose levels in prediabetic patients.

Weight loss elicits physiological adaptations that oppose ongoing weight loss.

Practitioners should consider physiological adaptations when advising clients on weight maintenance.

Treatment with SAR425899 resulted in a smaller reduction in body composition-adjusted sleeping metabolic rate (SMR) compared to placebo (p = 0.002).

SAR425899 may help mitigate metabolic adaptation during weight loss.

Fat oxidation and ketogenesis increased in both groups, with significantly greater increases in the SAR425899 group (p < 0.05).

SAR425899 may enhance fat metabolism, which could support weight loss efforts.

Both groups experienced an improvement in cardiometabolic risk markers after 12 months.

Improvements in cardiometabolic health may accompany weight loss in postmenopausal women.

Individuals with high skeletal muscle mitochondrial density (HI-CS) have higher VO(2)max and lower fasting respiratory quotient (RQ) compared to those with low mitochondrial density (LO-CS).

Higher mitochondrial density may enhance exercise capacity and metabolic efficiency in individuals.

Menopause leads to significant metabolic alterations and central and visceral fat redistribution in women.

Practitioners should be aware of the metabolic changes that occur during menopause and consider them in treatment strategies.

Changes in body composition at menopause influence risks of various health issues including cardiovascular disease and mental health disorders.

Health professionals should monitor and address the increased health risks associated with body composition changes during menopause.

Increased waist circumference (WC) during the first year of intensive lifestyle intervention (ILI) is associated with a higher risk for subsequent cardiovascular outcomes, independent of weight change.

Practitioners should monitor waist circumference in patients undergoing lifestyle interventions for diabetes management.

ILI participants with increased waist circumference had an increased risk of primary cardiovascular outcomes, regardless of weight loss or weight gain.

Weight management strategies should also focus on waist circumference reduction to mitigate cardiovascular risks.

Tirzepatide induced a mean absolute HbA1c reduction across the three doses ranging from 2.3% to 3.0% in East Asian participants with type 2 diabetes.

Tirzepatide is effective in reducing HbA1c levels in East Asian individuals with type 2 diabetes.

Metabolic adaptation plays a relevant role in the management of obesity and human weight loss.

Practitioners should consider metabolic adaptation when designing weight loss interventions.

GLP-1 receptor agonists (GLP-1 RAs) may improve obstructive sleep apnea (OSA) symptoms by reducing fat deposition around the upper airway and decreasing systemic inflammation.

Practitioners may consider GLP-1 RAs as a potential treatment option for improving OSA symptoms in obese patients.

GLP-1 RAs may enhance traditional OSA treatments, offering an integrated approach targeting the root cause of obesity in OSA.

Practitioners should consider integrating GLP-1 RAs into OSA management strategies.

GLP-1 RAs may provide benefits for other obesity-related comorbidities, including hypertension and cardiovascular disease.

Practitioners should be aware of the potential for GLP-1 RAs to address comorbidities in obese OSA patients.

Obesity contributes to the emergence of cardiovascular risk factors such as dyslipidaemia, type 2 diabetes, hypertension, and sleep disorders.

Addressing obesity may help in managing these associated cardiovascular risk factors.

Some researchers claim that the timing of nutritional consumption may be more critical to muscle development than the absolute daily consumption of nutrients.

Practitioners should consider the potential importance of nutrient timing in relation to total daily intake for muscle development.

Bariatric surgery before liver transplantation is feasible and can improve liver function for patients on the transplant waiting list.

Bariatric surgery may be a beneficial option for patients with obesity awaiting liver transplantation to enhance liver function.

A tendency toward a greater increase in fat-free mass (FFM) was observed in the OC group (3.7 ± 3.8%) compared to nonusers (2.7 ± 3.5%), with p = 0.08.

There may be a slight advantage in fat-free mass gain for OC users, warranting further investigation.

The intake of dairy appears to have a protective effect on some cardiovascular risk factors, or it is not worse than other SFA sources.

Incorporating dairy may be beneficial for cardiovascular health compared to other saturated fats.

Dairy products seem to present a different effect on cardiometabolic risk factors than other fat sources.

Understanding the unique effects of dairy can inform dietary recommendations regarding fat sources.